Thistle Mariano

Cardo MarianoSilybum marianum

Annual or hibernating plant, originating in the Mediterranean region, also grows in Central Europe, America and South Australia, in dry soils. Very cultivated. It is common in Portugal.

It is of the family Asteráceas (Composites) and the parts used are nuts (achenes).

It has a mixture of several flavanolinhanos isomers, called silymarin (silibina, silidianina, silicristina and others in smaller amount), flavonoids (beta-sitosterol, quercetin, campferol, taxifolina, apigenósido), fixed oil with a high proportion of linoleic, And palmitic, tocopherol and sterols.

Hepatoprotective verified in animal experimentation and in clinical studies due to the presence of silymarin that exerts a direct action on the hepatic parenchyma in case of intoxications. Silybin is a potent inhibitor of glutathione S-transferase. In venous circulatory problems it has antioxidant and antiradicalar action, hemostatic and venotonic.

Traditionally used in the treatment of support in inflammatory diseases of the liver and cirrhosis of the liver. As a hepatoprotective, to neutralize the effects of hepatotoxic substances.

If you wish, you can find more information about Taraxac in the scientific studies and literature that we provide:

Kalantari H. et al. (2011). Effects of silybum marianum on patients with chronic hepatitis C. Journal of Research in Medical Sciences 16 (3): 287-290.

Ghaffari AR et al. (2011). The effects of milk thistle in hepatic fibrosis due to methotrexate in rat. Hepatitis Monthly 11 (6): 464-468.

Skottová N and Krecman V (1998). Silymarin as a Potential Hypocholesterolaemic Drug. Physiological Research 47: 1-7.

Luper S (1998). A Review of Plants Used in the Treatment of Liver Disease: Part 1. Alternative Medicine Review 3 (6): 410-421.

Chen IS et al. (2012). Hepatoprotection of silymarin against thioacetamide-induced chronic liver fibrosis. Journal of the Science of Food and Agriculture 92 (7): 1441-1447.

Muthumani M and Prabu SM (2012). Silibinin potentially protects arsenic induced oxidative hepatic dysfunction in rats. Toxicology Mechanisms and Methods 22 (4): 277-288.

Das SJ and Mukherjee S (2012). Biochemical and immunological basis of silymarin effect, a milk thistle (Silybum marianum) against ethanol-induced oxidative damage. Toxicology Mechanisms and Methods 22 (5): 409-413.

Yormaz S et al. (2012). The comparison of the effects of hepatic regeneration after partial hepatectomy, silybum marinaum, propofol, N-acetylcysteine and vitamin E on liver. Bratislavske Lekarske Lysti 113 (3): 145-151.

Chtourou Y et al. (2012). Therapeutic efficacy of silymarin from milk thistle in reducing manganese-induced hepatic damage and apoptosis in rats. Human and Experimental Toxicology. [Epub ahead of print].



Cunha AP, Silva AP, Roque OR (2012). Plantas e Produtos Vegetais em Fitoterapia, 4ª Edição, Fundação Calouste Gulbenkian Serviço de Educação e Bolsas, 198-199.

Cunha AP, Roque OR (2011). Plantas Medicinais da Farmacopeia Portuguesa, 2ª Edição, Fundação Calouste Gulbenkian Serviço de Educação e Bolsas, 183-191.

Physicians Desk Reference for Herbal Medicines (2000), 2nd Edition, Thomson Medical Economics, 516-520.

Domínguez M, Gómez R. Novo Guia das Plantas Medicinais, Ediclube,77-78.



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